Infections in the Immunocomprised Host, vol.269, 2017. ,
Colonization of skin by Helcococcus kunzii, J Clin 270 Microbiol, vol.35, pp.2759-61, 1997. ,
Identification and Clinical Significance of Helcococcus 272 kunzii in Human Samples, J Clin Microbiol, vol.53, pp.2703-2708, 2015. ,
In vitro antimicrobial susceptibility of Helcococcus 274 kunzii and molecular analysis of macrolide and tetracycline resistance, Eur J Clin Microbiol 275 Infect Dis, vol.34, pp.2057-61, 2015. ,
Novel chromosome-encoded erm(47) determinant 277 responsible for constitutive MLS B resistance in Helcococcus kunzii, J Antimicrob Chemother, vol.278, pp.3046-3055, 2016. ,
Update on macrolide-lincosamide-streptogramin, ketolide, and oxazolidinone 280 resistance genes, FEMS Microbiol Lett, vol.282, pp.147-59, 2008. ,
Erythromycin resistance by ribosome modification, Antimicrob Agents 282 Chemother, vol.39, pp.577-85, 1995. ,
Site of action of a ribosomal RNA methylase responsible 284 for resistance to erythromycin and other antibiotics, J Biol Chem, vol.258, pp.12702-12708, 1983. ,
Methylation of 23S ribosomal RNA due to carB, an antibiotic-286 resistance determinant from the carbomycin producer, Streptomyces thermotolerans, Eur J 287 Biochem, vol.189, pp.67-72, 1990. ,
Activity of the ketolide antibiotic telithromycin is refractory to Erm 289 monomethylation of bacterial rRNA, Antimicrob Agents Chemother, vol.46, pp.1629-1662, 2002. ,
In vitro activity of the new ketolide 291 telithromycin compared with those of macrolides against Streptococcus pyogenes: influences 292 of resistance mechanisms and methodological factors, Antimicrob Agents Chemother, vol.293, pp.2999-3002, 2000. ,
Ketolide resistance in Streptococcus pyogenes correlates 295 with the degree of rRNA dimethylation by Erm, Mol Microbiol, vol.58, pp.613-635, 2005. ,
A novel Erm monomethyltransferase in antibiotic-297 resistant isolates of Mannheimia haemolytica and Pasteurella multocida, Mol Microbiol, vol.298, pp.184-94, 2011. ,
Deregulation of translation due to post-300 transcriptional modification of rRNA explains why erm genes are inducible, Nat Commun, vol.301, 1984. ,
The mechanism of action of macrolides, lincosamides 303 and streptogramin B reveals the nascent peptide exit path in the ribosome, J Mol Biol, vol.304, pp.1005-1019, 2003. ,
Induction of erythromycin resistance in Staphyloccus 306 aureus by erythromycin derivatives, Antimicrob Agents Chemother, vol.9, pp.128-158, 1976. ,
Molecular mechanism of drug-dependent ribosome 308 stalling, Mol Cell, vol.30, pp.190-202, 2008. ,
Synthesis and antibacterial activity of ketolides (6-O-310 methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against 311 macrolide-resistant and -susceptible respiratory pathogens, J Med Chem, vol.41, pp.4080-100, 1998. ,
The ketolides: a critical review, Drugs, vol.62, pp.313-1771, 2002. ,
Drug sensing by the ribosome induces translational 315 arrest via active site perturbation, Mol Cell, vol.56, pp.446-52, 2014. ,
Ribosome-Targeting Antibiotics: Modes of Action, p.317 ,
, Mechanisms of Resistance, and Implications for Drug Design, Annu Rev Biochem, vol.87, pp.318-451, 2018.
Ribosome-targeting antibiotics and mechanisms of bacterial resistance, Nat Rev 320 Microbiol, vol.12, pp.35-48, 2014. ,
A novel partial modification at 2501 in Escherichia coli 322 23S ribosomal RNA, RNA, vol.10, pp.907-920, 2004. ,
Identifying modifications in RNA by maldi mass spectrometry, Method Enzymol, vol.324, pp.3-20, 2007. ,
Computational prediction of RNA secondary structure, Methods Enzymol, vol.326, pp.3-65, 2013. ,
Improved estimation of secondary structure in 328 ribonucleic acids, Nat New Biol, vol.246, pp.40-41, 1973. ,
Mapping posttranscriptional modifications in 5S 330 ribosomal RNA by MALDI mass spectrometry, RNA, vol.6, pp.296-306, 2000. ,
, Weisblum B. Insights into erythromycin action from studies of its activity as inducer of 332 resistance, Antimicrob Agents Chemother, vol.39, pp.797-805, 1995.
Resistance to ketolide antibiotics by coordinated 334 expression of rRNA methyltransferases in a bacterial producer of natural ketolides, Proc Natl, vol.335 ,
, , vol.112, pp.12956-61, 2015.
mRNA helicase activity of the ribosome, Cell, vol.120, pp.337-386, 2005. ,
The general mode of translation inhibition by 339 macrolide antibiotics, Proc Natl Acad Sci U S A, vol.111, pp.15958-63, 2014. ,
Sequence selectivity of macrolide-induced translational 341 attenuation, Proc Natl Acad Sci U S A, vol.111, pp.15379-84, 2014. ,
Programmed drug-dependent ribosome stalling, Mol 343 Microbiol, vol.71, pp.811-835, 2009. ,
Context-specific inhibition of translation by ribosomal 345 antibiotics targeting the peptidyl transferase center, Proc Natl Acad Sci U S A, vol.113, pp.346-12150, 2016. ,
Lessons from an evolving rRNA: 16S and 23S rRNA 348 structures from a comparative perspective, Microbiol Rev, vol.58, pp.10-26, 1994. ,
, Noller HF. Structure of ribosomal RNA, Annual Review of Biochemistry, vol.53, pp.119-62, 1984.