L. H. Andersen, T. N. Kristensen, V. Loeschcke, S. Toft, and D. Mayntz, Protein and carbohydrate 465 composition of larval food affects tolerance to thermal stress and desiccation in adult Drosophila 466 melanogaster, Journal of Insect Physiology, vol.56, pp.336-340, 2010.

,

G. A. Armstrong, E. C. Rodríguez, and R. Meldrum-robertson, Cold hardening modulates K+ 469 homeostasis in the brain of Drosophila melanogaster during chill coma, Journal of Insect 470 Physiology, vol.58, pp.1511-1516, 2012.

E. L. Arrese and J. L. Soulages, Insect Fat Body: Energy, Metabolism, and Regulation, Annual 472 Review of Entomology, vol.55, pp.207-225, 2010.

F. Bäckhed, H. Ding, T. Wang, L. V. Hooper, G. Y. Koh et al., The gut microbiota as an environmental factor that regulates fat storage, PNAS, vol.474, pp.475-15718, 2004.

J. W. Ballard, R. G. Melvin, and S. J. Simpson, Starvation resistance is positively correlated with 477 body lipid proportion in five wild caught Drosophila simulans populations, Journal of Insect 478 Physiology, vol.54, pp.1371-1376, 2008.

A. Bartke, J. C. Wright, J. A. Mattison, D. K. Ingram, R. A. Miller et al., Extending the 480 lifespan of long-lived mice, Nature, vol.414, pp.412-412, 2001.

X. Bing, J. Gerlach, G. Loeb, and N. Buchon, Nutrient-Dependent Impact of Microbes on 482, 2018.

D. Drosophila-suzukii, , vol.9, pp.2199-2216

M. L. Koyle, M. Veloz, A. M. Judd, A. C. Wong, .. Newell et al., 594 Rearing the Fruit Fly Drosophila melanogaster Under Axenic and Gnotobiotic Conditions, 2016.

. Jove, Journal of Visualized Experiments, pp.54219-54219

T. N. Kristensen, A. K. Henningsen, C. Aastrup, M. Bech-hansen, L. B. Bjerre et al., , p.597

M. Hagstrup, S. G. Jensen, P. Karlsen, L. Kristensen, C. Lundsgaard et al., , p.598

L. D. Starcke, C. Sørensen, C. R. Schou, and M. F. , Fitness components of Drosophila 599 melanogaster developed on a standard laboratory diet or a typical natural food source, vol.23, pp.771-779, 2016.

S. Layalle, N. Arquier, and P. Léopold, The TOR Pathway Couples Nutrition and Developmental 602 Timing in Drosophila, Developmental Cell, vol.15, pp.568-577, 2008.

,

L. Bourg, E. Gauthier, T. Colinet, and H. , Feeding on frozen live yeast has some deleterious effects 605 in Drosophila melanogaster, Experimental Gerontology, vol.69, pp.202-210, 2015.

,

M. Le-rohellec and E. Le-bourg, Contrasted effects of suppressing live yeast from food on 608 longevity, aging and resistance to several stresses in Drosophila melanogaster, Exp. Gerontol, vol.609, pp.695-707, 2009.

K. P. Lee and T. Jang, Exploring the nutritional basis of starvation resistance in Drosophila 611 melanogaster, Functional Ecology, vol.28, pp.1144-1155, 2014.

K. P. Lee, S. J. Simpson, F. J. Clissold, R. Brooks, J. W. Ballard et al., , p.613

D. Raubenheimer, Lifespan and reproduction in Drosophila: New insights from 614 nutritional geometry, PNAS, vol.105, pp.2498-2503, 2008.

R. Leitão-gonçalves, Z. Carvalho-santos, A. P. Francisco, G. T. Fioreze, M. Anjos et al., , p.616

A. P. Elias, P. M. Itskov, M. D. Piper, and C. Ribeiro, Commensal bacteria and essential 617 amino acids control food choice behavior and reproduction, PLOS Biology, vol.15, 2017.

J. R. Lighton and L. G. Halsey, Flow-through respirometry applied to chamber systems: Pros and 620 cons, hints and tips. Comparative Biochemistry and Physiology Part A: Molecular & Integrative 621 Physiology, The challenge of measuring energy expenditure: current field and laboratory 622 methods 158, pp.265-275, 2011.

W. Mair, M. D. Piper, and L. Partridge, Calories do not explain extension of life span by dietary 624 restriction in Drosophila, PLoS Biol, vol.3, 2005.

E. J. Masoro, Caloric Restriction: A Key to Understanding and Modulating Aging, vol.1, 2003.

R. C. Matos, M. Schwarzer, H. Gervais, P. Courtin, P. Joncour et al., , p.628

M. E. Martino, S. Hughes, M. Chapot-chartier, and F. Leulier, D-Alanylation of teichoic 629 acids contributes to Lactobacillus plantarum -mediated Drosophila growth during chronic 630 undernutrition, Nature Microbiology, vol.2, pp.1635-1647, 2017.

L. M. Matzkin, S. Johnson, C. Paight, G. Bozinovic, and T. A. Markow, Dietary Protein and Sugar 633 Differentially Affect Development and Metabolic Pools in Ecologically Diverse Drosophila, J 634 Nutr, vol.141, pp.1127-1133, 2011.

K. Min, T. Flatt, I. Kulaots, and M. Tatar, Counting calories in Drosophila diet restriction, 2007.

, Experimental Gerontology, vol.42, pp.247-251

N. N. Moghadam, P. M. Thorshauge, T. N. Kristensen, N. Jonge, . De et al., , p.638

J. L. Nielsen, Strong responses of Drosophila melanogaster microbiota to developmental 639 temperature, Fly, vol.12, pp.1-12, 2018.

C. B. Montllor, A. Maxmen, and A. H. Purcell, Facultative bacterial endosymbionts benefit pea 641 aphids Acyrthosiphon pisum under heat stress, Ecological Entomology, vol.27, pp.189-195, 2002.

,

L. P. Musselman, J. L. Fink, K. Narzinski, P. V. Ramachandran, S. S. Hathiramani et al., , p.644

T. J. Baranski, A high-sugar diet produces obesity and insulin resistance in wild-type 645, 2011.

. Drosophila, Disease Models & Mechanisms, vol.4, pp.842-849

P. D. Newell and A. E. Douglas, Interspecies Interactions Determine the Impact of the Gut Microbiota 647 on Nutrient Allocation in Drosophila melanogaster, Appl. Environ. Microbiol, vol.80, pp.788-796, 2014.

J. Overgaard and H. A. Macmillan, The Integrative Physiology of Insect Chill Tolerance, Physiology, vol.79, pp.187-208, 2017.

. R-core-team, R: A language and environment for statistical computing. R Foundation for 652 Statistical Computing, 2017.

D. Raubenheimer, S. J. Simpson, and D. Mayntz, Nutrition, ecology and nutritional ecology: toward 654 an integrated framework, Functional Ecology, vol.23, pp.4-16, 2009.

E. V. Ridley, A. C. Wong, .. Westmiller, S. Douglas, and A. E. , Impact of the Resident Microbiota 657 on the Nutritional Phenotype of Drosophila melanogaster, PLOS ONE, vol.7, 2012.

S. Rion and T. J. Kawecki, Evolutionary biology of starvation resistance: what we have learned from 660, 2007.

. Drosophila, Journal of Evolutionary Biology, vol.20, pp.1655-1664

B. Rogina, S. L. Helfand, and S. Frankel, Longevity Regulation by Drosophila Rpd3 Deacetylase 663 and Caloric Restriction, Science, vol.298, pp.1745-1745, 2002.

J. A. Russell and N. A. Moran, Costs and benefits of symbiont infection in aphids: variation among 665 symbionts and across temperatures, Proceedings of the Royal Society of London B: Biological 666 Sciences, vol.273, pp.603-610, 2006.

D. R. Sannino, A. J. Dobson, K. Edwards, E. R. Angert, and N. Buchon, The Drosophila 668 melanogaster Gut Microbiota Provisions Thiamine to Its Host, vol.9, pp.155-173, 2018.

S. C. Shin, S. Kim, H. You, B. Kim, A. C. Kim et al., Drosophila microbiome modulates host developmental and metabolic homeostasis via 672 insulin signaling, Science, vol.334, pp.670-674, 2011.

F. H. Simmons and T. J. Bradley, An analysis of resource allocation in response to dietary yeast in 674 Drosophila melanogaster, Journal of Insect Physiology, vol.43, pp.779-788, 1997.

, , pp.37-38

S. J. Simpson and D. Raubenheimer, The Nature of Nutrition: A Unifying Framework from Animal 677 Adaptation to Human Obesity, 2012.

S. J. Simpson, G. A. Sword, P. D. Lorch, and I. D. Couzin, Cannibal crickets on a forced march for 679 protein and salt, PNAS, vol.103, pp.4152-4156, 2006.

S. Sisodia and B. N. Singh, Experimental Evidence for Nutrition Regulated Stress Resistance in 681, 2012.

. Drosophila-ananassae, PLOS ONE, vol.7

D. A. Skorupa, A. Dervisefendic, J. Zwiener, and S. D. Pletcher, Dietary composition specifies 683 consumption, obesity, and lifespan in Drosophila melanogaster, Aging Cell, vol.7, pp.478-490, 2008.

S. M. Solon-biet, A. C. Mcmahon, J. W. Ballard, K. Ruohonen, L. E. Wu et al., , p.687

D. A. Sinclair, D. Raubenheimer, D. G. Le-couteur, and S. J. Simpson, The Ratio of 688, 2014.

. Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in 689 Ad Libitum-Fed Mice, Cell Metabolism, vol.19, pp.418-430

,

G. Storelli, A. Defaye, B. Erkosar, P. Hols, J. Royet et al., Lactobacillus plantarum 692 promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent 693 nutrient sensing, Cell Metab, vol.14, pp.403-414, 2011.

M. A. Téfit, B. Gillet, P. Joncour, S. Hughes, and F. Leulier, Stable association of a Drosophila-695 derived microbiota with its animal partner and the nutritional environment throughout a fly 696 population's life cycle, Journal of Insect Physiology, vol.106, pp.2-12, 2018.

J. M. Tennessen, W. E. Barry, J. Cox, and C. S. Thummel, , p.699, 2014.

, Drosophila. Methods, Drosophila developmental biology methods, vol.68, pp.105-115

,

A. C. Wong, .. Dobson, A. J. Douglas, and A. E. , Gut microbiota dictates the metabolic response of 702 Drosophila to diet, Journal of Experimental Biology, vol.217, pp.1894-1901, 2014.

R. Yamada, S. A. Deshpande, K. D. Bruce, E. M. Mak, and W. W. Ja, Microbes Promote Amino Acid 705 Harvest to Rescue Undernutrition in Drosophila, Cell Reports, vol.10, pp.865-872, 2015.

,

C. Zhu, P. Ingelmo, and D. M. Rand, G×G×E for Lifespan in Drosophila: Mitochondrial, Nuclear, 708 and Dietary Interactions that Modify Longevity, PLOS Genetics, vol.10, 2014.