Long-term outcome of patients with non-operated prosthetic valve infective endocarditis is relapse the main issue?

Raphaël Lecomte (1, 2) , Jean-Baptiste Laine (1, 2) , Nahéma Issa (3) , Matthieu Revest (4, 5, 6) , Benjamin Gaborit (1, 2) , Paul Le Turnier (2, 1) , Colin Deschanvres (2, 1) , François Benezit (4) , Nathalie Asseray (1) , Thierry Le Tourneau , Sabine Pattier , Ousama Al Habash (2) , François Raffi (2) , David Boutoille (2) , Fabrice Camou (3)

1 CIC Nantes - Centre d’Investigation Clinique de Nantes
2 CHU Nantes - Centre hospitalier universitaire de Nantes
3 Groupe hospitalier Saint-André
4 CHU Pontchaillou [Rennes]
5 CIC - Centre d'Investigation Clinique [Rennes]
6 BRM - ARN régulateurs bactériens et médecine

In non-operated prosthetic valve endocarditis (PVE), long term outcome is largely unknown. We report the follow-up of 129 non-operated patients with PVE alive at discharge. At one year, the mortality rate was 24%, relapses and reinfection were rare (5% each). Enterococcal PVE was associated with a higher risk of relapse.

Keywords: Relapse; Infective endocarditis; Surgery; Prosthetic valve

Domains: Life Sciences [q-bio]; Human health and pathology; Cardiology and cardiovascular system; Life Sciences [q-bio]; Human health and pathology; Infectious diseases; Life Sciences [q-bio]; Human health and pathology; Surgery

Raphaël Lecomte, Jean-Baptiste Laine, Nahéma Issa, Matthieu Revest, Benjamin Gaborit, et al.. Long-term outcome of patients with non-operated prosthetic valve infective endocarditis is relapse the main issue?. Clinical Infectious Diseases, 2020, 71 (5), pp.1316-1319. ⟨10.1093/cid/ciz1177⟩. ⟨hal-02440778⟩