W. C. Hembree, G. G. Nahas, P. Zeidenberg, and H. F. Huang, Changes in human spermatozoa associated with high dose marihuana smoking, Adv. Biosci, pp.429-468, 1978.

S. E. Lewis, Differences in the endocannabinoid system of sperm from fertile and infertile men, PLoS One, vol.7, 2012.

T. D. Gundersen, Association between use of marijuana and male reproductive hormones and semen quality: A study among 1,215 healthy young men, Am. J. Epidemiol, vol.182, pp.473-481, 2015.

P. Hsiao and R. I. Clavijo, Adverse effects of Cannabis on male reproduction, Eur Urol. Focus, vol.4, pp.324-328, 2018.

J. R. Daling, Association of marijuana use and the incidence of testicular germ cell tumors, Cancer, vol.115, pp.1215-1223, 2009.

J. Gurney, C. Shaw, J. Stanley, V. Signal, and D. Sarfati, Cannabis exposure and risk of testicular cancer: a systematic review and metaanalysis, BMC Cancer, vol.15, 2015.

R. G. Pertwee, Endocannabinoids and their pharmacological actions, Handbook of Experimental Pharmacology, vol.231, pp.1-37, 2015.

A. Ligresti, L. De-petrocellis, and V. Di-marzo, From phytocannabinoids to cannabinoid receptors and endocannabinoids: Pleiotropic physiological and pathological roles through complex pharmacology, Physiol. Rev, vol.96, pp.1593-1659, 2016.

A. C. Howlett, The cannabinoid receptors, Prostaglandins Other Lipid. Mediat, pp.619-631, 2002.

E. Ryberg, The orphan receptor GPR55 is a novel cannabinoid receptor, Br. J. Pharmacol, vol.152, pp.1092-1101, 2007.

P. Bovolin, Endocannabinoids are involved in male vertebrate reproduction: Regulatory mechanisms at central and gonadal level, Front. Endocrinol. (Lausanne), vol.5, 2014.

M. C. Gye, H. H. Kang, and H. J. Kang, Expression of cannabinoid receptor 1 in mouse testes, Arch. Androl, vol.51, pp.247-55, 2005.

T. Chioccarelli, Cannabinoid receptor 1 influences chromatin remodeling in mouse spermatids by affecting content of transition protein 2 mRNA and histone displacement, Endocrinology, vol.151, pp.5017-5046, 2010.

G. Cacciola, Low 17beta-estradiol levels in CNR1 knock-out mice affect spermatid chromatin remodeling by interfering with chromatin reorganization, Biol. Reprod, vol.88, 2013.

P. Grimaldi, The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis, Proc. Natl. Acad. Sci. USA, vol.106, pp.11131-11136, 2009.

T. Wenger, C. Ledent, V. Csernus, and I. Gerendai, The central cannabinoid receptor inactivation suppresses endocrine reproductive functions, Biochem. Biophys. Res. Commun, vol.284, pp.363-368, 2001.

M. Rossato, F. Ion-popa, M. Ferigo, G. Clari, and C. Foresta, Human sperm express cannabinoid receptor Cb1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function, J Clin Endocrinol Metab, vol.90, pp.984-991, 2005.

F. Francavilla, Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability, Endocrinology, vol.150, pp.4692-4700, 2009.

E. Agirregoitia, The CB(2) cannabinoid receptor regulates human sperm cell motility, Fertil. Steril, vol.93, pp.1378-1387, 2010.

A. Barbonetti, Involvement of cannabinoid receptor-1 activation in mitochondrial depolarizing effect of lipopolysaccharide in human spermatozoa, Andrology, vol.2, pp.502-509, 2014.

M. R. Miller, Unconventional endocannabinoid signalling governs sperm activation via the sex hormone progesterone, Science, vol.352, pp.555-559, 2016.

M. M. Francou, Human sperm motility, capacitation and acrosome reaction are impaired by 2-arachidonoylglycerol endocannabinoid, Histol Histopathol, vol.32, pp.1351-1358, 2017.

C. M. Gérard, C. Mollereau, G. Vassart, and M. Parmentier, Molecular cloning of a human cannabinoid receptor which is also expressed in testis, Biochem. J, vol.279, pp.129-134, 1991.

E. Ryberg, Identification and characterisation of a novel splice variant of the human CB1 receptor, FEBS Letters, vol.579, pp.259-264, 2005.

Q. R. Liu, Species differences in cannabinoid receptor 2 (CNR2 gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands, Genes Brain Behav, vol.8, pp.519-530, 2009.

B. Jégou, S. Sankararaman, A. D. Rolland, D. Reich, and F. Chalmel, Meiotic genes are enriched in regions of reduced archaic ancestry, Mol. Biol. Evol, vol.34, 1974.

P. Grimaldi, D. Di-giacomo, and R. Geremia, The endocannabinoid system and spermatogenesis, Front. Endocrinol. (Lausanne), vol.4, 2013.

M. Migliaccio, Analysis of Endocannabinoid System in Rat Testis During the First Spermatogenetic Wave, Front. Endocrinol. (Lausanne), vol.29, 2018.

M. Uhlén, Proteomics. Tissue-based map of the human proteome, Science, vol.347, p.1260419, 2015.

H. Schuel, N-Acylethanolamines in human reproductive fluids, Chem. Phys. Lipids, vol.121, pp.211-227, 2002.

A. A. Amoako, Anandamide modulates human sperm motility: implications for men with asthenozoospermia and oligoasthenoteratozoospermia, Hum. Reprod, vol.28, pp.2058-2066, 2013.

A. Barbonetti, 2-arachidonoylglycerol levels are increased in leukocytospermia and correlate with seminal macrophages, Andrology, vol.5, pp.87-94, 2017.

G. Cobellis, Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells, Biol. Reprod, vol.75, pp.82-89, 2006.

D. Giacomo, D. De-domenico, E. Sette, C. Geremia, R. Grimaldi et al., Type 2 cannabinoid receptor contributes to the physiological regulation of spermatogenesis, FASEB J, vol.30, pp.1453-1463, 2016.

V. K. Bhosle, F. Gobeil, J. C. Rivera, A. Ribeiro-da-silva, and S. Chemtob, High resolution imaging and function of nuclear G protein-coupled receptors (GPCRs), Methods Mol. Biol, vol.1234, pp.81-97, 2015.

J. Hu, F. Sun, and M. A. Handel, Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice, Biol Reprod, vol.98, pp.102-114, 2018.

G. Ricci, Endocannabinoid control of sperm motility: the role of epididymus, Gen Comp Endocrinol, vol.153, pp.320-322, 2007.

G. Cobellis, A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up, Biol Reprod, vol.82, issue.2, pp.451-459, 2010.

W. Hall and M. Weier, Assessing the public health impacts of legalizing recreational cannabis use in the USA, Clin. Pharmacol. Ther, vol.97, pp.607-615, 2015.

E. Rajpert-de-meyts, J. E. Nielsen, N. E. Skakkebaek, and K. Almstrup, Diagnostic markers for germ cell neoplasms: from placentallike alkaline phosphatase to micro-RNAs, Folia Histochem. Cytobiol, vol.53, pp.177-188, 2015.

A. Jørgensen, Hanging-drop cultures of human testis and testis cancer samples: a model used to investigate activin treatment effects in a preserved niche, Br J Cancer, vol.110, issue.10, pp.2604-2618, 2014.

R. T. Mitchell, Xenografting of human fetal testis tissue: a new approach to study fetal testis development and germ cell differentiation, Hum. Reprod, vol.25, pp.2405-2414, 2010.

F. Chalmel, High-resolution profiling of novel transcribed regions during rat spermatogenesis, Biol. Reprod, vol.91, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01063924

C. Zimmermann, Research resource: the dynamic transcriptional profile of Sertoli cells during the progression of spermatogenesis, Mol. Endocrinol, vol.29, pp.627-642, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01146846

J. Pollier, S. Rombauts, and A. Goossens, Analysis of RNA-Seq data with TopHat and Cufflinks for genome-wide expression analysis of jasmonate-treated plants and plant cultures, Methods Mol. Biol, vol.1011, pp.305-315, 2013.

N. A. O'leary, Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation, Nucleic Acids Res, vol.44, issue.D1, pp.733-745, 2016.

T. A. Darde, The ReproGenomics Viewer: an integrative cross-species toolbox for the reproductive science community, Nucleic Acids Res, vol.43, issue.W1, pp.109-116, 2015.
URL : https://hal.archives-ouvertes.fr/hal-02445074

T. Svingen, A. Jørgensen, and E. Rajpert-de-meyts, Validation of endogenous normalizing genes for expression analyses in adult human testis and germ cell neoplasms, Mol. Hum. Reprod, vol.20, pp.709-718, 2014.

T. Schramm, imzML-a common data format for the flexible exchange and processing of mass spectrometry imaging data, J. Proteomics, vol.75, pp.5106-5110, 2012.
URL : https://hal.archives-ouvertes.fr/hal-00741330

G. Robichaud, K. P. Garrard, J. A. Barry, and D. C. Muddiman, MSiReader: an open-source interface to view and analyze high resolving power MS imaging files on Matlab platform, J. Am. Soc. Mass. Spectrom, vol.24, pp.718-721, 2013.