Activating natural cytotoxicity receptors of natural killer cells in cancer and infection, Trends Immunol, vol.34, pp.182-191, 2013. ,
Regulation of the functions of natural cytotoxicity receptors by interactions with diverse ligands and alterations in splice variant expression, Front Immunol, vol.8, p.369, 2017. ,
The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans, J Exp Med, vol.206, pp.1495-1503, 2009. ,
Tumor therapeutics work as stress inducers to enhance tumor sensitivity to Natural Killer (NK) cell cytolysis by up-regulating NKp30 ligand B7-H6, J Biol Chem, vol.290, pp.29964-29973, 2015. ,
Group 2 innate lymphoid cells express functional NKp30 receptor inducing type 2 cytokine production, J Immunol, vol.196, pp.45-54, 2016. ,
Induction of B7-H6, a ligand for the natural killer cell-activating receptor NKp30, in inflammatory conditions, Blood, vol.122, pp.394-404, 2013. ,
Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation, 2017. ,
Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20, Sci Rep, vol.7, p.8661, 2017. ,
Human Herpesvirus 6B Downregulates expression of activating ligands during lytic infection to escape elimination by natural killer cells, J Virol, vol.90, pp.9608-9617, 2016. ,
B7-H6-mediated downregulation of NKp30 in natural killer cells contributes to HIV-2 immune escape, AIDS, vol.33, pp.23-32, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-02307134
B7H6-specific chimeric antigen receptors lead to tumor elimination and host antitumor immunity, Gene Ther, vol.22, pp.675-684, 2015. ,
B7H6-specific bispecific T cell engagers Lead to tumor elimination and host antitumor immunity, J Immunol, vol.194, pp.5305-5311, 2015. ,
The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells, Oncoimmunology, vol.5, p.1116674, 2016. ,
Long non-coding RNA LINC00673 promotes breast cancer proliferation and metastasis through regulating B7-H6 and epithelial-mesenchymal transition, Am J Cancer Res, vol.8, pp.1273-1287, 2018. ,
Proteostasis control by the unfolded protein response, Nat Cell Biol, vol.17, pp.829-838, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01175531
Signal integration in the endoplasmic reticulum unfolded protein response, Nat Rev Mol Cell Biol, vol.8, pp.519-529, 2007. ,
The integrated stress response, EMBO Rep, vol.17, pp.1374-1395, 2016. ,
Regulated translation initiation controls stress-induced gene expression in mammalian cells, Mol Cell, vol.6, pp.1099-1108, 2000. ,
Widespread PERK-dependent repression of ER targets in response to ER stress, Sci Rep, vol.9, p.4330, 2019. ,
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1, Nat Immunol, vol.4, pp.321-329, 2003. ,
, , 2018.
, Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation, Genome Med, vol.10, p.76
The impact of the endoplasmic reticulum protein-folding environment on cancer development, Nat Rev Cancer, vol.14, pp.581-597, 2014. ,
Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation, J Exp Med, vol.214, pp.2985-2997, 2017. ,
Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1, FASEB J, vol.33, pp.3481-3495, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-01940305
A systematic view on influenza induced host shutoff, 2016. ,
Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-p yrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), J Med Chem, vol.55, pp.7193-7207, 2012. ,
Pharmacological brake-release of mRNA translation enhances cognitive memory, vol.2, p.498, 2013. ,
A unique ISR program determines cellular responses to chronic stress, Mol Cell, vol.68, p.886, 2017. ,
The human cytomegalovirus endoplasmic reticulumresident glycoprotein UL148 activates the unfolded protein response, J Virol, vol.92, 2018. ,
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis, Science, vol.332, pp.91-94, 2011. ,
The eIF2alpha/ATF4 pathway is essential for stress-induced autophagy gene expression, Nucleic Acids Res, vol.41, pp.7683-7699, 2013. ,
An inhibitor of HIV-1 protease modulates constitutive eIF2alpha dephosphorylation to trigger a specific integrated stress response, Proc Natl Acad Sci U S A, vol.113, pp.117-126, 2016. ,
HIV protease inhibitors sensitize human head and neck squamous carcinoma cells to radiation by activating endoplasmic reticulum stress, PLoS One, vol.10, p.125928, 2015. ,
Pharmacokinetics and safety of nelfinavir when used in combination with zidovudine and lamivudine in HIV-infected pregnant women: pediatric AIDS Clinical Trials Group (PACTG) protocol 353, HIV Clin Trials, vol.9, pp.115-125, 2008. ,
A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors, Oncotarget, vol.5, pp.8161-8172, 2014. ,
Treatment with the HIV protease inhibitor nelfinavir triggers the unfolded protein response and may overcome proteasome inhibitor resistance of multiple myeloma in combination with bortezomib: a phase I trial (SAKK 65/08), Haematologica, vol.101, pp.346-355, 2016. ,
Immunotherapy in melanoma: recent advances and future directions, Eur J Surg Oncol, vol.43, pp.604-611, 2017. ,
The future of immune checkpoint therapy, Science, vol.348, pp.56-61, 2015. ,
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth, J Clin Invest, vol.122, pp.4621-4634, 2012. ,
Activation of the PERK-ATF4 pathway promotes chemoresistance in colon cancer cells, Sci Rep, vol.9, p.3210, 2019. ,
PERK is a Haploinsufficient tumor suppressor: gene dose determines tumor-suppressive versus tumor promoting properties of PERK in melanoma, PLoS Genet, vol.12, p.1006518, 2016. ,
Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation, J Biol Chem, vol.286, pp.10939-10949, 2011. ,
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response, J Cell Biol, vol.167, pp.27-33, 2004. ,
Translation from the 5' untranslated region shapes the integrated stress response, Science, vol.351, p.3867, 2016. ,
HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells, Gastroenterology, vol.138, pp.197-209, 2010. ,
Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2alpha-ATF4-xCT pathway, Oncotarget, vol.7, pp.74132-74151, 2016. ,
The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling, Science, vol.365, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-02372326
Multi targeted CAR-T cell therapies for B-cell malignancies, Front Oncol, vol.9, p.146, 2019. ,
Axicabtagene Ciloleucel CAR T-cell therapy in refractory large B-cell lymphoma, N Engl J Med, vol.377, pp.2531-2544, 2017. ,
Mechanisms of resistance to CAR T cell therapy, Nat Rev Clin Oncol, vol.16, pp.372-385, 2019. ,
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