Synthesis, intermolecular interactions and biological activities of two new organic-inorganic hybrids C6H10N2,2Br and C6H10N2,2Cl .H2O

Intissar Hamdi (1) , Intidhar Bkhairia (1) , Andreas Roodt (2) , Thierry Roisnel (3) , Moncef Nasri (4) , Houcine Naili (1)

1 Université de Sfax - University of Sfax
2 UFS - University of the Free State [South Africa]
3 ISCR - Institut des Sciences Chimiques de Rennes
4 ENIS - École Nationale d'Ingénieurs de Sfax | National School of Engineers of Sfax

A slow evaporation method has permitted the crystallization of two novel crystals of (2-aminomethyl)pyridindiumdihalide C6H10N2,2Br (1) and C6H10N2,2Cl center dot H2O (2). The structures of the prepared compounds (1) and (2) were elucidated by single-crystal X-ray diffraction which revealed that they crystallize, respectively, with triclinic and monoclinic symmetries. Their crystal packing was stabilized by non-covalent interactions, including N-HMIDLINE HORIZONTAL ELLIPSISBr, C-HMIDLINE HORIZONTAL ELLIPSISBr, N-HMIDLINE HORIZONTAL ELLIPSISCl, O-HMIDLINE HORIZONTAL ELLIPSISCl and N-HMIDLINE HORIZONTAL ELLIPSISO hydrogen bonds. 3-D Hirshfeld surface analysis followed by 2-D fingerprint schemes gives insights into the intermolecular interactions in the crystalline structure. Furthermore, the FT-IR spectroscopy of these two compounds was carried out. The synthesized products were also screened for in vitro antioxidant and antimicrobial activities, which reveals their favourable antioxidant activities against 1,1-diphenyl-2-picrylhydrazyl (DPPH) as well as the discolouration of beta-carotene.

Domaines: Chimie

Intissar Hamdi, Intidhar Bkhairia, Andreas Roodt, Thierry Roisnel, Moncef Nasri, et al.. Synthesis, intermolecular interactions and biological activities of two new organic-inorganic hybrids C6H10N2,2Br and C6H10N2,2Cl .H2O. RSC Advances, 2020, 10 (10), pp.5864-5873. ⟨10.1039/c9ra09294c⟩. ⟨hal-02531288⟩