Tabagisme pendant la grossesse : impact sur l’enfant, de la naissance à l’âge adulte — Rapport d’experts et recommandations CNGOF-SFT sur la prise en charge du tabagisme en cours de grossesse

Héloïse Torchin (1, 2) , M Le Lous (3) , V Houdouin (4)

1 AP-HP - Hôpital Cochin Broca Hôtel Dieu [Paris]
2 CRESS (U1153 / UMR_A 1125) - Centre for Research in Epidemiology and Statistics | Centre de Recherche Épidémiologie et Statistiques
3 LTSI - Laboratoire Traitement du Signal et de l'Image
4 HIPI (UMR_S_976 / U976) - Immunologie humaine, physiopathologie & immunothérapie

Introduction - Smoking during pregnancy leads to fetal passive smoking. It is associated with several obstetrical complications and is a major modifiable factor of maternal and fetal morbidity. Long-term consequences also exist but are less well known to health professionals and in the general population. Methods - Consultation of the Medline® database. Results - Maternal smoking during pregnancy is associated in the offspring with sudden infant death syndrome (NP2), impaired lung function (NP2), lower respiratory infections and asthma (NP2), overweight and obesity (NP2), cancers (NP3), risk of tobacco use, nicotine dependence and early smoking initiation (NP2). Unadjusted analyses show associations between in utero tobacco exposure and cognitive deficits (NP3), impaired school performance (NP3) and behavioral disorders in children (NP2), which are in a large part explained by environmental factors. There is a cross-generational effect of smoking during pregnancy. For example, an increased risk of asthma is observed in the grandchildren of smoking women (NP4). The respective roles of ante- and post-natal smoking remain difficult to assess. Conclusion - These results highlight the importance of prevention measures against tobacco use in the general population, as well as screening measures and support for smoking cessation before or at the beginning of the pregnancy.

Mots clés: Tabagisme pendant la grossesse; Santé de l’enfant; Mort inattendue du nourrisson; Complications respiratoires; Troubles du développement

Domaines: Ingénierie biomédicale; Gynécologie et obstétrique

Héloïse Torchin, M Le Lous, V Houdouin. Tabagisme pendant la grossesse : impact sur l’enfant, de la naissance à l’âge adulte — Rapport d’experts et recommandations CNGOF-SFT sur la prise en charge du tabagisme en cours de grossesse. Gynécologie Obstétrique Fertilité & Sénologie, 2020, 48 (7-8), pp.567-577. ⟨10.1016/j.gofs.2020.03.026⟩. ⟨hal-02563158⟩