The rising burden of cancer in the developing world, Ann Oncol, vol.17, pp.15-23, 2006. ,
Recent advances in cancer therapy: an overview, Curr Pharm Des, vol.16, pp.3-10, 2010. ,
Global burden of cancers attributable to infections in 2012: a synthetic analysis, Lancet Glob Health, vol.4, pp.609-616, 2016. ,
Infections in Cancer Patients with Solid Tumors: A Review, Infect Dis Ther, vol.6, pp.69-83, 2017. ,
Antibiotics and bacterial resistance in the 21st century, Perspect Medicin Chem, vol.6, pp.25-64, 2014. ,
Next-generation metal anticancer complexes: multitargeting via redox modulation, Inorg Chem, vol.52, pp.12276-12291, 2013. ,
Metallodrugs in medicinal inorganic chemistry, Chem Rev, vol.114, pp.4540-4563, 2014. ,
,
Fighting cancer with transition metal complexes: from naked DNA to Protein and Chromatin Targeting Strategies, ChemMedChem, vol.11, pp.1199-1210, 2016. ,
Effects of monofunctional platinum agents on bacterial growth: a retrospective study, J Am Chem Soc, vol.136, pp.116-118, 2014. ,
,
Antimicrobial spectrum of the antitumor agent, cisplatin, J Antibiot, vol.63, pp.530-532, 2010. ,
Platinum antitumor complexes: 50 years since Barnett Rosenberg's discovery, J Clin Oncol, vol.33, pp.4219-4226, 2015. ,
Cisplatin in cancer therapy: molecular mechanisms of action, Eur J Pharmacol, vol.740, pp.364-378, 2014. ,
,
Drug resistance in cancer: an overview Cancers (Basel), vol.6, pp.1769-1792, 2014. ,
Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapy, Radiol Oncol, vol.53, pp.148-158, 2019. ,
Ruthenium complexes as antimicrobial agents, Chem Soc Rev, vol.44, pp.2529-2542, 2015. ,
Synthesis, spectral, antitumor and antimicrobial studies on Cu(II) complexes of purine and triazole Schiff base derivatives, J Mol Struc, vol.1049, pp.326-335, 2013. ,
Heteroleptic oxidovanadium(IV) complexes of 2-hydroxynaphtylaldimine and polypyridyl ligands against Trypanosoma cruzi and prostate cancer cells, J Inorg Biochem, vol.175, pp.154-166, 2017. ,
Pharmacological activity of a few transition metal complexes: a short review, Chem Biol Ther, vol.1, p.108, 2016. ,
Chemical biology of anticancer gold(III) and gold(I) complexes, Chem Soc Rev, vol.44, pp.8786-8801, 2015. ,
Phosphine-gold(I) compounds as anticancer agents: general description and mechanisms of action, Anticancer Agents Med Chem, vol.11, pp.921-928, 2011. ,
New insights in Au-NHCs complexes as anticancer agents, Eur J Med Chem, vol.146, pp.709-746, 2018. ,
,
Gold(I) complexes with thiosemicarbazones: cytotoxicity against human tumor cell lines and inhibition of thioredoxin reductase activity, J Inorg Biochem, vol.105, pp.1729-1739, 2011. ,
Synthesis, structures and anti-malaria activity of some gold(I) phosphine complexes containing seleno-and thiosemicarbazonato ligands, Dalton Trans, vol.40, pp.9810-9820, 2011. ,
Gold compounds for rheumatoid arthritis, Gold Bull, vol.19, pp.15-16, 1986. ,
Unique properties of auranofin as a potential antirheumatic drug, Agents Actions, vol.19, pp.109-115, 1986. ,
,
Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia, Cancer Res, vol.74, pp.2520-2532, 2014. ,
Auranofin: repurposing an old drug for a golden new age, Drugs R D, vol.15, pp.13-20, 2015. ,
,
Selection and characterization of a human ovarian cancer cell line resistant to auranofin, Oncotarget, vol.8, pp.96062-96078, 2017. ,
,
Potent and selective cytotoxic and anti-inflammatory gold(III) compounds containing cyclometalated phosphine sulfide ligands, Chem Eur J, vol.25, pp.14089-14100, 2019. ,
,
New Variations on the Theme of Gold(III) C?N?N Cyclometalated Complexes as Anticancer Agents: Synthesis and Biological Characterization, Inorg Chem, vol.57, pp.14852-14865, 2018. ,
Towards the rational design of platinum(II) and gold(III) complexes as antitumour agents, pp.1521-1532, 2008. ,
Gold(III) complexes in medicinal chemistry Future Med Chem, vol.6, pp.1515-1536, 2014. ,
Noble metals in medicine: latest advances, Coord Chem Rev, vol.284, pp.329-350, 2015. ,
Gold-based medicine: A paradigm shift in anti-cancer therapy? Molecules, vol.23, p.1410, 2018. ,
, Medicinal Chemistry of Gold Anticancer Metallodrugs, p.18, 2018.
Gold(III) complexes for antitumor applications: an overview, Chemistry, vol.4, pp.11840-11851, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01947213
Cyclometallated Au(III) dithiocarbamate complexes: synthesis, anticancer evaluation and mechanistic studies, Metallomics, vol.10, pp.1655-1666, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01947032
Gold compounds as therapeutic agents for human diseases, Metallomics, vol.3, pp.863-873, 2011. ,
Gold complexes as antimicrobial agents: an overview of different biological activities in relation to the oxidation state of the gold ion and the ligand structure, vol.43, pp.5950-5969, 2014. ,
,
Antimicrobial activity of silver camphorimine complexes against Candida strains, Antibiotics, vol.8, p.144, 2019. ,
, Antibiotic Resistance: Global Report on Surveillance, World Health Organization, 2014.
,
Structural, electrical, magnetic, and optical properties of bisbenzene-1,2-dithiolato-Au(IV) crystals, Phys Rev B, vol.53, pp.1773-1778, 1996. ,
,
Gold complexes with dithiothiophene digands: A metal based on a neutral molecule, Chem Eur J, vol.7, pp.511-519, 2001. ,
,
Stable metallic state of a neutral radical single-component conductor at ambient pressure, J Am Chem Soc, vol.140, pp.6998-7004, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01807877
,
Anisotropic Chemical Pressure Effects in Single-Component Molecular Metals Based on Thiazole Dithiolate and Diselenolate Gold Complexes, J Am Chem Soc, vol.134, pp.17138-17148, 2012. ,
Transition metal complexes based on thiophene-dithiolene ligands, Coord Chem Rev, vol.254, pp.1479-1492, 2010. ,
Au(pyb-H)(mnt)]: A novel gold(III) 1,2-dithiolene cyclometalated complex with antimicrobial activity (pyb-H=C-deprotonated 2-benzylpyridine; mnt=1,2-dicyanoethene-1,2-dithiolate), J Inorg Biochem, vol.170, pp.188-194, 2017. ,
Dithiolenes and non-innocent redox-active ligands, Coord Chem Rev, vol.254, pp.1357-1588, 2010. ,
,
On the path to gold: monoanionic Au bisdithiolate complexes with antimicrobial and antitumor activities, J Inorg Biochem, vol.202, p.110904, 2020. ,
URL : https://hal.archives-ouvertes.fr/hal-02364867
,
A single-component molecular metal based on a thiazole dithiolate gold complex, J Am Chem Soc, vol.131, pp.16961-16967, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-01151145
Subtle steric differences impact the structural and conducting properties of radical gold bis(dithiolene) complexes, Chem Eur J, vol.23, pp.16004-16013, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01636555
Hydrogen bonding interactions in a single component molecular conductor: hydroxyethylsubstituted radical gold dithiolene complex, Inorg Chem, vol.53, pp.8755-8761, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01151681
,
Gold and nickel alkyl substituted bis-thiophenedithiolene complexes: anionic and neutral forms Inorg Chem Front, vol.4, pp.270-280, 2017. ,
Antifungal resistance: a concerning trend for the present and future, Curr Infect Dis Rep, vol.21, p.47, 2019. ,
In vitro cytotoxicity assays: comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride, Toxicol Lett, vol.160, pp.171-177, 2006. ,
,
Antibacterial activity of silver camphorimine coordination polymers, Dalton Trans, vol.45, pp.7114-7123, 2016. ,
EUCAST technical note on the EUCAST definitive document EDef 7.2: method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef, EUCAST-AFST), vol.7, pp.246-247, 2012. ,
Susceptibility testing: accurate and reproducible minimum inhibitory concentration (MIC) and non-inhibitory concentration (NIC) values, J Appl Microbiol, vol.88, pp.784-790, 2000. ,
,
,
Franke-Fayard, Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging, PLoS ONE, vol.4, p.7881, 2009. ,
Quality assurance of X-ray spectrometry for chemical analysis, Spectrochimica Acta Part B-Atomic Spectroscopy, vol.56, pp.2095-2106, 2001. ,
Quantitation of DNA and RNA with absorption and fluorescence spectroscopy, Current Protocols in Molecular Biology, 1994. ,
Ribonuclease T1 and alcohol dehydrogenase fluorescence quenching by acrylamide: A laboratory experiment for undergraduate students, J Chem Educ, vol.70, pp.425-428, 1993. ,
Experimental correction for the inner-filter effect in fluorescence-spectra, Analyst, vol.119, pp.417-419, 1994. ,
, Principles of Fluorescence Spectroscopy, 3rd, 2006.
Ligand-solvent interactions in a highly reduced metal chelate complex: medium dependence of the one-electron reduction of the bis(maleonitriledithiolato)gold dianion, Inorg Chem, vol.48, pp.10826-10836, 2009. ,
A Sulfur rich electron acceptor and its [Fe(Cp*)2]+ charge transfer salt with ferromagnetic interactions, vol.42, pp.16672-16679, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-00908601
,
Auranofin efficacy against MDR Streptococcus pneumoniae and Staphylococcus aureus infections, J Antimicrob Chemother, vol.70, pp.2608-2617, 2015. ,
,
Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis, Proc Natl Acad Sci, vol.112, pp.4453-4458, 2015. ,
Influence of DMSO on antifungal activity during susceptibility testing in vitro, Diagn Microbiol Infect Dis, vol.75, pp.60-63, 2013. ,
,
Repurposing approach identifies auranofin with broad spectrum antifungal activity that targets Mia40-Erv1 pathway, Front Cell Infect Microbiol, vol.7, p.4, 2017. ,
A toolbox to study liver stage malaria, Trends Parasitol, vol.27, pp.565-574, 2011. ,
,
Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug, J Infect Dis, vol.205, pp.1278-1286, 2012. ,
, Novel inhibitors of the Plasmodium falciparum electron transport chain, vol.141, pp.50-65, 2014.
,
,
Antimalarial activity of primaquine operates via a two-step biochemical relay, Nat Commun, vol.10, p.3226, 2019. ,
Primaquine revisited six decades after its discovery, Eur J Med Chem, vol.44, pp.937-953, 2009. ,
Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs, Coord Chem Rev, vol.253, pp.1692-1707, 2009. ,
Metal-and semimetal-containing inhibitors of thioredoxin reductase as anticancer agents, Molecules, vol.20, pp.12732-12756, 2015. ,
Small molecule inhibitors of mammalian thioredoxin reductase as potential anticancer agents: An update, Med Res Rev, vol.39, pp.5-39, 2019. ,
, Methods Enzymol, vol.252, pp.199-208, 1995.
Mechanism of ethidium bromide fluorescence enhancement on binding to nucleic acids, Biochemistry, vol.16, pp.3647-3654, 1977. ,
, Graphical Abstract (synopsis)
III) bis(dithiolene) complexes were evaluated as therapeutic drugs ,