Regioselective glycosylation: What's new?

Laurent Legentil (1, 2) , Vincent Ferrières (1, 2)

1 ENSCR - Ecole Nationale Supérieure de Chimie de Rennes
2 ISCR - Institut des Sciences Chimiques de Rennes

The aim of this chapter is to show how increased understanding of the mechanisms related to both carbohydrate-processing enzymes and intrinsic properties of monoglycosyl residue have significantly impacted our way of thinking about the glycosylation reaction. A focus is made on the importance of low energy interactions. Some recent examples related to biocatalytic approaches and chemical synthesis are given.

Domaines: Chimie

Laurent Legentil, Vincent Ferrières. Regioselective glycosylation: What's new?. Carbohydrate Chemistry, 43, Royal Society of Chemistry, pp.104-134, 2018, Carbohydrate Chemistry, ⟨10.1039/9781788010641-00104⟩. ⟨hal-03657428⟩