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The current state of clinical mycology in Africa: a European Confederation of Medical Mycology and International Society for Human and Animal Mycology survey

Abstract : Africa, although not unique in this context, is a favourable environment for fungal infections, given the high burden of risk factors. An online survey was developed asking about laboratory infrastructure and antifungal drug availability. We received 40 responses (24.4% response rate) of 164 researchers contacted from 21 African countries. Only five institutions (12.5%) of 40 located in Cameroon, Kenya, Nigeria, Sudan, and Uganda potentially fulfilled the minimum laboratory requirements for European Confederation of Medical Mycology Excellence Centre blue status. Difficulties included low access to susceptibility testing for both yeasts and moulds (available in only 30% of institutions) and Aspergillus spp antigen detection (available in only 47.5% of institutions as an in-house or outsourced test), as well as access to mould-active antifungal drugs such as amphotericin B deoxycholate (available for 52.5% of institutions), itraconazole (52.5%), voriconazole (35.0%), and posaconazole (5.0%). United and targeted efforts are crucial to face the growing challenges in clinical mycology.
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https://hal.archives-ouvertes.fr/hal-03788516
Contributor : Laurent Jonchère Connect in order to contact the contributor
Submitted on : Monday, September 26, 2022 - 4:41:56 PM
Last modification on : Thursday, December 1, 2022 - 1:58:04 PM

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Distributed under a Creative Commons Attribution - NonCommercial - NoDerivatives 4.0 International License

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Cândida Driemeyer, Diego R Falci, Rita O Oladele, Felix Bongomin, Bright K. Ocansey, et al.. The current state of clinical mycology in Africa: a European Confederation of Medical Mycology and International Society for Human and Animal Mycology survey. Lancet Microbe, 2022, 3 (6), pp.E464-E470. ⟨10.1016/S2666-5247(21)00190-7⟩. ⟨hal-03788516⟩

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