Layer 2/3 Pyramidal Neurons Control the Gain of Cortical Output

Michael Quiquempoix (1, 2) , Sophie L Fayad (1, 2) , Katia Boutourlinsky (1, 2) , Nathalie Leresche (1, 2) , Régis C. Lambert (1, 2) , Thomas Bessaïh (1, 2)

1 IBPS - Institut de Biologie Paris Seine
2 NPS - Réseaux de neurones et rythmes physiopathologiques = Neuronal Networks and Physiopathological Rhythms

Graphical Abstract Highlights d Cortical layer 2/3 (L2/3) input evokes both excitatory and inhibitory currents in L5 d L2/3 input has a net excitatory effect in L5 d L2/3 input amplifies sensory-evoked responses in L5 d L2/3 input modulates the gain of sensory-evoked responses in L5

Domaines: Neurobiologie

Michael Quiquempoix, Sophie L Fayad, Katia Boutourlinsky, Nathalie Leresche, Régis C. Lambert, et al.. Layer 2/3 Pyramidal Neurons Control the Gain of Cortical Output. Cell Reports, 2018, 24 (11), pp.2799 - 2807.e4. ⟨10.1016/j.celrep.2018.08.038⟩. ⟨hal-01892557⟩