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Journal articles
Palladium-Catalyzed Cascade sp(2) C-H Bond Functionalizations Allowing One-Pot Access to 4-Aryl-1,2,3,4-tetrahydroquinolines from N-Allyl-N-arylsulfonamides
Abstract : We have developed a palladium-catalyzed cascade reaction allowing an efficient synthesis of 4-aryl-1,2,3,4-tetrahydroquinolines from N-allyl-N-arylsulfonamides and benzenesulfonyl chlorides. In this transformation, two C(sp(2))-C(sp(3)) bonds were formed via activation of C(sp(2))-H bonds. The reaction proceeds using the easily accessible catalyst PdCl2, with Li2CO3 as inexpensive base and CuBr as additive, and tolerates a wide variety of substituents on both reaction partners.
Cited literature [8 references]
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01438127
Contributor : Laurent Jonchère <>
Submitted on : Thursday, July 13, 2017 - 12:00:47 PM
Last modification on : Wednesday, January 13, 2021 - 3:13:27 AM
Long-term archiving on: : Thursday, January 25, 2018 - 1:45:13 AM
Contributor : Laurent Jonchère <>
Submitted on : Thursday, July 13, 2017 - 12:00:47 PM
Last modification on : Wednesday, January 13, 2021 - 3:13:27 AM
Long-term archiving on: : Thursday, January 25, 2018 - 1:45:13 AM