Pure phosphotriesters as versatile ligands in transition metal catalysis: efficient hydrosilylation of ketones and diethylzinc addition to aldehydes

M. Bouhachicha (1) , A. Ngo Ndimba (1) , Thierry Roisnel (1) , Claudia Lalli (1) , G. Argouarch (1)

1 ISCR - Institut des Sciences Chimiques de Rennes

This work aims to highlight the underrated role played by pure phosphotriester (or phosphate) ligands in catalysis, when compared to other phosphorus-containing donors such as phosphane oxides or phosphites. To probe this and to enlarge the very narrow catalytic scope of these Lewis bases, easily accessible mono-and bidentate phosphotriesters were tested as donors in two important transition metal-based catalytic transformations: the zinc-catalyzed hydrosilylation of ketones and the titanium-promoted diethylzinc addition to aldehydes. In both cases, the reactions were successful and the corresponding alcohols were obtained in high yields.

Domaines: Catalyse

M. Bouhachicha, A. Ngo Ndimba, Thierry Roisnel, Claudia Lalli, G. Argouarch. Pure phosphotriesters as versatile ligands in transition metal catalysis: efficient hydrosilylation of ketones and diethylzinc addition to aldehydes. New Journal of Chemistry, 2017, 41 (12), pp.4767--4770. ⟨10.1039/c7nj00566k⟩. ⟨hal-01559213⟩