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How to quantify hepatic steatosis?

Abstract : The frequency of hepatic steatosis in the population and its potential complications require knowing how to diagnose and quantify this lesion in clinical practice. Ultrasound allows semi-quantification based on the liver/kidney signal ratio. The CT scanner has a marginal rule, mainly before surgery of resection and before transplantation. MRI is the technique of choice for quantification, using simple multi-echo techniques and manufacturer or free softwares like MRQuantif. The quantification of steatosis in MRI should always be associated with iron quantification to avoid errors. The discovery of steatosis must systematically lead to the search for hepatic fibrosis, at best at the same time using ultrasonore elastometry. Incidental finding of steatosis must be semi-quantified and noted in the report. The indications to look after hepatic steatosis are the existence of liver biological abnormalities, obesity, type 2 diabetes, metabolic syndrome or the existence of cardiovascular risks. In this situation, ultrasound technic is recommended for the evaluation of steatosis. When accurate quantification of steatosis is required, the currently recommended tool is MRI with the multi-echo technique.
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Submitted on : Thursday, September 27, 2018 - 2:46:48 PM
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Christophe Aubé, Anita Paisant, Jérôme Lebigot, Yves Gandon. How to quantify hepatic steatosis?. Journal d'imagerie diagnostique et interventionnelle, 2018, 1 (2), pp.92-96. ⟨10.1016/j.jidi.2017.12.003⟩. ⟨hal-01882859⟩



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