Twofold Ferrocene C-H Lithiations For One-Step Difunctionalizations

William Erb (1) , Florence Mongin (1)

1 ISCR - Institut des Sciences Chimiques de Rennes

For some aromatics, a twofold C–H deprotolithiation can be achieved, allowing these compounds to be subsequently difunctionalized in one step. This short review brings together examples in which ferrocenes are converted in this way.

Mots clés: chiral ligand; chiral directing group; planar chirality; ferrocene; electrophilic trapping; deprotolithiation; dilithio compounds; ferrocenophane

Domaines: Chimie de coordination

William Erb, Florence Mongin. Twofold Ferrocene C-H Lithiations For One-Step Difunctionalizations. Synthesis: Journal of Synthetic Organic Chemistry, 2019, 51 (1), pp.146-160. ⟨10.1055/s-0037-1610396⟩. ⟨hal-01997977⟩