Skip to Main content Skip to Navigation
Journal articles

Functionalization of pyridyl ketones using deprotolithiation-in situ zincation

Abstract : The metallation of aryl ketones was achieved by using LiTMP in the presence of ZnCl2 center dot TMEDA, as evidenced by subsequent interception with iodine or by a palladium-catalysed cross-coupling reaction. One of the synthesized iodo ketones has been further elaborated to reach derivatives of biological interest.
Document type :
Journal articles
Complete list of metadata

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01357392
Contributor : Laurent Jonchère Connect in order to contact the contributor
Submitted on : Tuesday, June 28, 2022 - 4:44:39 PM
Last modification on : Thursday, August 4, 2022 - 5:28:54 PM

File

main met ketones Erb Mongin HA...
Files produced by the author(s)

Identifiers

Citation

Madani Hedidi, William Erb, Frédéric Lassagne, Yury S. Halauko, Oleg A. Ivashkevich, et al.. Functionalization of pyridyl ketones using deprotolithiation-in situ zincation. RSC Advances, Royal Society of Chemistry, 2016, 6 (68), pp.63185--63189. ⟨10.1039/c6ra11370b⟩. ⟨hal-01357392⟩

Share

Metrics

Record views

106

Files downloads

0